ASSESSMENT OF THE INSTRUMENTAL ACTIVITIES OF DAILY LIVING IN MILD COGNITIVE IMPAIRMENT AND DEMENTIA DUE TO ALZHEIMER'S DISEASE: DIAGNOSTIC ACCURACY OF THE SERBIAN VERSION OF THE AMSTERDAM IADL QUESTIONNAIRE

To establish a diagnosis of dementia, it is necessary, in addition to cognitive impairment, prove the existence disorder instrumental activities daily living (IADL). The Amsterdam IADL Questionnaire reliable instrument translated into different languages. This study aims assess diagnostic accuracy Serbian version Questionnaire. included 75 patients with mild impairment (MCI) and dementia due Alzheimer's disease. questionnaire was scored using weighted average (WA) item response theory (IRT) scoring method. Diagnostic examined receiver–operating characteristic (ROC) curves. area under curves (AUC) calculated 95% confidence intervals (CI). correlation between IRT WA scores strong significant (r=-0.980, p<0.001). AUC for A-IADL-Q 0.832 (95% CI: 0.729 0.909), while 0.848 0.746 0.920). Both were significantly from 0.5 (p<0.001). There no difference AUCs (z=1.157; p=0.247). Cutoffs highest combination sensitivity specificity (sensitivity 0.767; 0. 844) 0.744; calculated. We have shown that has moderate differentiating MCI. can be used measures diagnose its early stages.